MRI-ARSACS: An Imaging Index for Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS) Identification Based on the Multicenter PROSPAX Study.
Alessandra ScaravilliDavide NegroniClaudio SenatoreLorenzo UggaMirco CosottiniIvana RiccaBenjamin BenderAndreas TraschützAyse Nazli BasakAtay VuralBart P van de WarrenburgAlexandra DurrRoberta La PianaDagmar Timmannnull nullRebecca SchüleMatthis SynofzikFilippo Maria SantorelliSirio CocozzaPublished in: Movement disorders : official journal of the Movement Disorder Society (2024)
Evaluation of the pons-to-superior vermis area ratio can discriminate ARSACS from other SPAX patients, as exemplified here by SPG7. Hence, we hereby propose this ratio as the Magnetic Resonance Index for the Assessment and Recognition of patients harboring SACS mutations (MRI-ARSACS), a novel diagnostic tool able to identify ARSACS patients and useful for discriminating ARSACS from other SPAX patients undergoing MRI. © 2024 International Parkinson and Movement Disorder Society.
Keyphrases
- end stage renal disease
- magnetic resonance
- ejection fraction
- newly diagnosed
- magnetic resonance imaging
- patients undergoing
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- peritoneal dialysis
- contrast enhanced
- clinical trial
- computed tomography
- cross sectional
- diffusion weighted imaging
- early onset
- duchenne muscular dystrophy
- botulinum toxin
- upper limb
- clinical evaluation