Human galectin-9 on the porcine cells affects the cytotoxic activity of M1-differentiated THP-1 cells through inducing a shift in M2-differentiated THP-1 cells.

Sung Han JungJeong Ho HwangSang Eun KimYoung Kyu KimHyo Chang ParkHoon Taek Lee

Published in: Xenotransplantation (2017)

These data suggested that hGal-9 has a reduction in M1-differentiated THP-1 cell cytotoxic activity-related acute immune rejection in pig-to-human xenotransplantation in addition to its role in lymphoid lineage immune cell regulation.

Keyphrases

induced apoptosis
cell cycle arrest
endothelial cells
single cell
oxidative stress
stem cells
bone marrow
mesenchymal stem cells
hepatitis b virus
artificial intelligence
cell therapy
pluripotent stem cells
deep learning
acute respiratory distress syndrome
anti inflammatory