Membrane metalloendopeptidase (MME) is positively correlated with systemic lupus erythematosus and may inhibit the occurrence of breast cancer.
Jiatong DingChenxi LiKexin ShuWanying ChenChenxi CaiXin ZhangWenxiong ZhangPublished in: PloS one (2023)
In summary, MME expression was significantly decreased in BRCA but positively correlated with SLE, and it might reduce the incidence of BRCA in SLE patients via the PI3K/AKT/FOXO signaling pathway.
Keyphrases
- systemic lupus erythematosus
- signaling pathway
- disease activity
- ejection fraction
- newly diagnosed
- pi k akt
- poor prognosis
- prognostic factors
- risk factors
- rheumatoid arthritis
- transcription factor
- oxidative stress
- induced apoptosis
- binding protein
- patient reported outcomes
- young adults
- long non coding rna
- cell proliferation