A Severe Case of Streptococcus pneumoniae Meningoencephalitis in an Infant Resulting in Fatal Strokes.
Michelle GoodmanMekka R GarciaHeidy WangMaria J BorjaClaire MillerDevorah SegalPublished in: Child neurology open (2024)
Streptococcus pneumoniae (S. Pneumoniae) is a common cause of bacterial meningitis in the pediatric population, but rarely causes complications such as encephalitis, abscess, and seizures with the prompt initiation of proper antimicrobial therapy. In this report, we present a rare and severe case of S. Pneumoniae meningoencephalitis in a full term 6-month-old which progressed to multiple cerebral and cerebellar infarcts with concomitant cerebellar tonsillar herniation and hypercarbic respiratory failure requiring intubation and mechanical ventilation despite early initiation of antibiotics. Given the patient's clinical status and poor neurological prognosis, the family eventually opted for palliative extubation.
Keyphrases
- mechanical ventilation
- respiratory failure
- acute respiratory distress syndrome
- intensive care unit
- extracorporeal membrane oxygenation
- early onset
- staphylococcus aureus
- case report
- cardiac arrest
- palliative care
- preterm infants
- subarachnoid hemorrhage
- cerebrospinal fluid
- drug induced
- gestational age
- stem cells
- advanced cancer
- bone marrow
- brain injury
- mesenchymal stem cells
- blood brain barrier