Evening Primrose Extract Modulates TYMS Expression via SP1 Transcription Factor in Malignant Pleural Mesothelioma.

Malgorzata Chmielewska-Kassassir Katarzyna Sobierajska Wojciech Michał Ciszewski Jakub Kryczka Andrzej Zieleniak Lucyna Alicja Wozniak

Published in: Cancers (2023)

promoter and reversed the EMT phenotype of invasive MPM cells. Further in-depth analysis of the molecular docking of polyphenol compounds with SP1 regulatory motifs is required.

Keyphrases

molecular docking
transcription factor
induced apoptosis
molecular dynamics simulations
poor prognosis
cell cycle arrest
dna binding
oxidative stress
epithelial mesenchymal transition
dna methylation
gene expression
optical coherence tomography
signaling pathway
binding protein
genome wide identification