The Correlates & Public Health Consequences of Prospective Vaccine Hesitancy among Individuals Who Received COVID-19 Vaccine Boosters in the U.S.

Supplemental "booster" vaccines may prove vital in combating variant waves of endemic COVID-19. Given relatively low levels of booster vaccine uptake, Americans' willingness to receive a second booster shot is unclear. In a demographically representative survey of N = 3950 US adults (limited to a "boosted" subsample of N = 1551 who had not yet received a second booster), 49% [95% CI: 47, 51] of Americans report having received an initial booster shot, while just 34% [33, 36] report that they would be "very likely" to do so again. Concerns about missing work to vaccinate (-10%; B = 0.53, p = 0.05) and being unconvinced that additional boosters will be necessary (-47%; B = 2.24, p < 0.01) are significantly and negatively associated with being very likely to receive a second COVID-19 booster. These findings can help inform discussions about policies aimed at increasing vaccine uptake in the U.S., and broaden researchers' understanding of vaccine reluctance among those who might otherwise hold positive views toward vaccination.