Different clinical and genetic features of Alagille patients with progressive disease versus a jaundice-free course.
Che-Ming ChiangYung-Ming JengMing-Chih HoMing-Wei LaiHuei-Ying LiPei-Lung ChenHung-Chang LeeJia-Feng WuYu-Chun ChiuBang-Yu LiouYen-Hsuan NiHong-Yuan HsuMei-Hwei ChangHuey-Ling ChenPublished in: JGH open : an open access journal of gastroenterology and hepatology (2022)
One-third of ALGS patients had JF and a favorable course. Children with ALGS presenting with persistent jaundice beyond 2 years of age should be cautioned for poor prognosis. ALGS patients tend to have a lesser extent of cirrhosis, and more growth problems than BA patients at the time of LT.