Analysis of lncRNA-miRNA-mRNA expression pattern in heart tissue after total body radiation in a mouse model.

Molykutty J AryankalayilShannon MartelloMichelle A BylickySunita ChopraJared M MayAman ShankardassLaurel MacMillanLandy SunJaleal SanjakClaire Vanpouille-BoxIris EkeC Norman Coleman

Published in: Journal of translational medicine (2021)

Radiation-induced RNA expression changes may be predictive of normal tissue toxicities and may indicate targetable pathways for radiation countermeasure development and improved radiotherapy treatment plans.

Keyphrases

radiation induced
radiation therapy
mouse model
poor prognosis
heart failure
long non coding rna
early stage
squamous cell carcinoma
combination therapy