Rescuing SLAMF3 Expression Restores Sorafenib Response in Hepatocellular Carcinoma Cells through the Induction of Mesenchymal-to-Epithelial Transition.

Grégory FouquetConstance MariéLouison ColletCatherine VilpouxHakim Ouled-HaddouEric Nguyen-KhacJagadeesh BayryMickaël NaassilaIngrid MarcqHicham Bouhlal

Published in: Cancers (2022)

We propose that rescuing SLAMF3 expression in resistant cells could represent a potential therapeutic strategy to enhance sorafenib efficacy in HCC patients.

Keyphrases

poor prognosis
end stage renal disease
ejection fraction
induced apoptosis
newly diagnosed
chronic kidney disease
stem cells
bone marrow
peritoneal dialysis
long non coding rna
patient reported outcomes
signaling pathway
cell proliferation
oxidative stress
cell death