Obese Mice with Dyslipidemia Exhibit Meibomian Gland Hypertrophy and Alterations in Meibum Composition and Aqueous Tear Production.
Eugene Appenteng OsaeTiffany BullockMadhavi ChintapalatiSusanne BrodesserSamuel HanlonRachel RedfernPhilipp StevenC Wayne SmithRolando E RumbautAlan R BurnsPublished in: International journal of molecular sciences (2020)
The majority of meibum lipid species with saturated fatty acids increased with HFD feeding with evidence of meibomian gland hypertrophy and excessive tearing. The dyslipidemia is associated with altered meibum composition, a key feature of MGD.