Endovascular shedding markers in patients with heart failure with reduced ejection fraction: Results from a single-center exploratory study.
Petra NijstJirka CopsPieter MartensQuirine SwennenMatthias DupontWai Hong W TangWilfried MullensPublished in: Microcirculation (New York, N.Y. : 1994) (2018)
The glycocalyx shedding marker HA is significantly elevated in a subgroup of HFrEF patients and an independent predictor for worse clinical outcome. Glycocalyx shedding might be an additional factor in the pathophysiology of HF which warrants further investigation.