Plasma Level of ATPase Inhibitory Factor 1 (IF1) and intrinsic capacity in community-dwelling older adults: Prospective data from the MAPT Study.
Jaqueline Aragoni da SilvaLaurent O MartinezYves RollandSouad NajibMikaël CroyalBertrand PerretNabila Jabrane-FerratHicham El CostaSophie GuyonnetBruno VellasPhilipe de Souto Barretonull nullPublished in: The journals of gerontology. Series A, Biological sciences and medical sciences (2023)
This study is the first to demonstrate that levels of circulating IF1, a mitochondrial-related biomarker, are associated with IC composite scores in both cross-sectional and prospective analyses among community-dwelling older adults. However, further research is needed to confirm these findings and elucidate the potential underlying mechanisms that may explain these associations.