DLX6-AS1/miR-204-5p/OCT1 positive feedback loop promotes tumor progression and epithelial-mesenchymal transition in gastric cancer.

Yu LiangChun-Dong ZhangCheng ZhangDong-Qiu Dai

Published in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2019)

This study revealed that OCT1-induced DLX6-AS1 promoted GC progression and the EMT via the miR-204-5p/OCT1 axis, suggesting that this lncRNA might be a promising prognostic biomarker and therapeutic target for GC.

Keyphrases

epithelial mesenchymal transition
optical coherence tomography
diabetic retinopathy
transforming growth factor
optic nerve
signaling pathway
poor prognosis
high glucose
diabetic rats
gas chromatography
transcription factor
oxidative stress
mass spectrometry
long noncoding rna
drug induced
high resolution