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Single-cell sequencing unveils distinct immune microenvironments with CCR6-CCL20 crosstalk in human chronic pancreatitis.

Bomi LeeHong NamkoongYan YangHuang HuangDavid HellerGregory L SzotMark M DavisSohail Z HusainStephen Jacob PandolMelena D BellinAida Habtezion
Published in: Gut (2021)
Single-cell sequencing with pancreatic immune cells in human CP highlights pancreas-specific immune crosstalk through the CCR6-CCL20 axis, a signalling pathway that might be leveraged as a potential future target in human hereditary CP.
Keyphrases
  • single cell
  • endothelial cells
  • rna seq
  • induced pluripotent stem cells
  • pluripotent stem cells
  • high throughput
  • dendritic cells
  • liver fibrosis
  • liver injury
  • immune response
  • current status
  • risk assessment