Gene Expression and Immunochemistry Analysis of ADAMTS-1 and Versican in Ameloblastoma.

Osvaldo Rodrigues de Souza Neto Hellen Thais Fuzii Suély Vieira Da Silva Vanessa Morais Freitas João de Jesus Viana Pinheiro

Published in: International journal of dentistry (2022)

This study showed a distinct expression of ADAMTS-1 and versican in ameloblastoma and DF, with ADAMTS-1 protein higher expression observed in ameloblastoma and possibly cleaved versican. These findings suggested that ADAMTS-1 may participate in tumor invasion, especially for the degradation of substrates (versican) in the ECM.

Keyphrases

gene expression
poor prognosis
binding protein
dna methylation
long non coding rna