NLRP3 inflammasome expression in lipopolysaccharide-induced otitis media.

Shin KariyaMitsuhiro OkanoPengfei ZhaoYukihide MaedaYuko KataokaTakaya HigakiYohei NodaSeiichiro MakiharaKazunori Nishizaki

Published in: Acta oto-laryngologica (2019)

Lipopolysaccharide induces NLRP3 inflammasome components in the middle ear. The NLRP3 inflammasome may play an important role in the pathogenesis of otitis media. Modulation of inflammasome-mediated inflammation may be a novel therapeutic strategy for otitis media.

Keyphrases

nlrp inflammasome
lipopolysaccharide induced
inflammatory response
poor prognosis
oxidative stress
lps induced
toll like receptor
long non coding rna