Lipid Peroxidation and Antioxidant Consumption as Early Markers of Neurosurgery-Related Brain Injury in Children.
M PiastraE CarestaL MassimiE PicconiE LucaTony Christian MorenaG ContiS EatonPublished in: Neurocritical care (2021)
Our results indicate that lipid peroxidation increases consistently following brain surgery, and it is accompanied by a decrease in antioxidant defences; intraventricular catheterization offers a unique chance of oxidative process monitoring. Further studies are needed to evaluate whether monitoring post-neurosurgical oxidative stress in CSF is of prognostic utility.
Keyphrases
- brain injury
- oxidative stress
- subarachnoid hemorrhage
- cerebral ischemia
- minimally invasive
- anti inflammatory
- fatty acid
- diabetic rats
- young adults
- dna damage
- ischemia reperfusion injury
- white matter
- induced apoptosis
- coronary artery bypass
- resting state
- blood brain barrier
- atrial fibrillation
- multiple sclerosis
- acute coronary syndrome
- cerebrospinal fluid
- heat shock protein