Progesterone requires heat shock protein 90 (HSP90) in human sperm to regulate motility and acrosome reaction.
Vrushali Sagare-PatilRashmi BhilawadikarMosami GalvankarKusum ZaveriIndira HindujaDeepak N ModiPublished in: Journal of assisted reproduction and genetics (2017)
HSP90 levels are downregulated in oligoasthenozoospermia, and its functional inhibition attenuates progesterone-mediated sperm motility and acrosome reaction.