Pan-tissue transcriptome analysis of long noncoding RNAs in the American beaver Castor canadensis.

Amita KashyapAdelaide RhodesBrent KronmillerJosie BergerAshley ChampagneEdward W DavisMitchell V FinneganMatthew GenizaDavid A HendrixChristiane V LöhrVanessa M PetroThomas J SharptonJackson WellsClinton W EppsPankaj JaiswalBrett M TylerStephen A Ramsey

Published in: BMC genomics (2020)

To our knowledge this is the first report of systematic identification of lncRNAs and their expression atlas in beaver. LncRNAs-both novel and those with known orthologs-are expressed in each of the beaver tissues that we analyzed. For some beaver lncRNAs with known orthologs, the tissue-specific expression patterns were phylogenetically conserved. The lncRNA sequence data files and raw sequence files are available via the web supplement and the NCBI Sequence Read Archive, respectively.

Keyphrases

poor prognosis
network analysis
long non coding rna
healthcare
binding protein
genome wide analysis
gene expression
genome wide identification
electronic health record
deep learning
artificial intelligence