The prognostic value of JUNB-positive CTCs in metastatic breast cancer: from bioinformatics to phenotypic characterization.

Galatea KallergiVasileia TsintariStelios SfakianakisEkaterini BeiEleni LagoudakiAnastasios KoutsopoulosNefeli ZacharopoulouSaad AlkahtaniSaud AlarifiChristos StournarasMichalis ZervakisVassilis Georgoulias

Published in: Breast cancer research : BCR (2019)

CXCR4, JUNB, and TYROBP were overexpressed in CTCs, but only the expression of JUNB was associated with poor prognosis, providing a new biomarker and a potential therapeutic target for the elimination of CTCs.

Keyphrases

poor prognosis
circulating tumor cells
metastatic breast cancer
long non coding rna
human health
climate change
binding protein