Heparanase Inhibition Prevents Liver Steatosis in E 0 Mice.

Safa KinanehWalaa HijazeLana Mansour-WattadRawan HammoudHisam ZaidaniAviva KabalaShadi Hamoud

Published in: Journal of clinical medicine (2022)

Heparanase inhibition significantly attenuates the development of liver steatosis by decreasing tissue lipid content and by affecting the mRNA expression of key lipid metabolism regulators.

Keyphrases

high fat diet induced
insulin resistance
high fat diet
fatty acid
transcription factor
adipose tissue
mouse model
skeletal muscle