DNA methylation and single-nucleotide polymorphisms in DDX58 are associated with hand, foot and mouth disease caused by enterovirus 71.

Ya-Ping LiChen-Rui LiuHui-Ling DengMu-Qi WangYan TianYuan ChenYu-Feng ZhangShuang-Suo DangSong Zhai

Published in: PLoS neglected tropical diseases (2022)

DDX58 expression and promoter methylation were associated with EV71 infection progression, especially in severe EV71-HFMD patients. The effect of DDX58 in EV71-HFMD is worth further attention.

Keyphrases

dna methylation
end stage renal disease
genome wide
gene expression
newly diagnosed
ejection fraction
chronic kidney disease
poor prognosis
peritoneal dialysis
prognostic factors
working memory
transcription factor
early onset
copy number