Model-based meta-analysis of the time to first acute urinary retention or benign prostatic hyperplasia-related surgery in patients with moderate or severe symptoms.
Salvatore D'AgateChandrashekhar ChavanMichael ManyakJuan Manuel Palacios-MorenoMatthias OelkeMartin C MichelClaus G RoehrbornOscar Della PasquaPublished in: British journal of clinical pharmacology (2021)
Our analysis showed the implications of disease-modifying properties of dutasteride and tamsulosin-dutasteride combination therapy for the risk of AUR/S. It also elucidated the contribution of different baseline characteristics to the risk of these events. The use of tamsulosin monotherapy (symptomatic treatment) has no impact on individual long-term risk.
Keyphrases
- benign prostatic hyperplasia
- lower urinary tract symptoms
- systematic review
- minimally invasive
- drug induced
- combination therapy
- liver failure
- coronary artery bypass
- meta analyses
- early onset
- respiratory failure
- open label
- high intensity
- intensive care unit
- randomized controlled trial
- coronary artery disease
- physical activity
- aortic dissection
- clinical trial
- percutaneous coronary intervention
- acute coronary syndrome
- depressive symptoms
- smoking cessation
- double blind