Chronic restraint stress induces changes in the cerebral Galpha 12/13 and Rho-GTPase signaling network.

Katarzyna Rafa-Zabłocka Agnieszka Zelek-Molik Beata Tepper Piotr Chmielarz Grzegorz Kreiner Michał Wilczkowski Irena Nalepa

Published in: Pharmacological reports : PR (2021)

Together, these results suggest that repeated RS affects the expression of genes and proteins known to be engaged in neural plasticity, providing potential targets for further studies aimed at unraveling the molecular mechanisms of stress-related neuropsychiatric diseases.

Keyphrases

stress induced
poor prognosis
subarachnoid hemorrhage
gene expression
binding protein
risk assessment
case control
long non coding rna
protein kinase
human health
brain injury
network analysis