Pruritus is defined as a symptom that leads to scratching. Clinically, a heterogeneous group of clinical pictures of different etiology must be considered. Pruritus is characterized by varying intensity and duration. Many patients and/or their social environment, which is influenced by this, cite the impact on sleep quality as an accompanying main symptom. The patient's quality of life is affected depending on the severity of the pruritus and often leads to comorbidity such as depressive disorders or sleep disorders as well as to an impact on psychosocial well-being if it becomes chronic. To date, in addition to the medical history, the established examination methods have been the determination of the disease burden by assessing disease activity, e.g., with validated disease-specific scores, plus the assessment of quality of life using a dermatological quality of life index (DLQI). The latest studies show that this is by no means sufficient to determine the severity of disease and, as a result, to identify adequate treatment options.
Keyphrases
- sleep quality
- disease activity
- depressive symptoms
- rheumatoid arthritis
- systemic lupus erythematosus
- physical activity
- healthcare
- end stage renal disease
- atopic dermatitis
- mental health
- ejection fraction
- chronic kidney disease
- newly diagnosed
- ankylosing spondylitis
- rheumatoid arthritis patients
- peritoneal dialysis
- case report
- bipolar disorder
- juvenile idiopathic arthritis
- prognostic factors
- mass spectrometry
- risk factors
- high resolution
- molecularly imprinted
- solid phase extraction
- clinical evaluation