Production of highly polarized [1-13 C]acetate by rapid decarboxylation of [2-13 C]pyruvate - application to hyperpolarized cardiac spectroscopy and imaging.
Jonas SteinhauserPatrick WespiGrzegorz KwiatkowskiSebastian KozerkePublished in: Magnetic resonance in medicine (2019)
Decarboxylation of hyperpolarized [2-13 C]pyruvate enables the efficient production of highly polarized [1-13 C]acetate that is applicable to study short-chain fatty acid metabolism in the in vivo heart.