Risperidone plasma concentrations are associated with side effects and effectiveness in children and adolescents with autism spectrum disorder.
Sanne Maartje KloosterboerBrenda C M de WinterCatrien G ReichartMirjam E J KouijzerMatthias M J de KroonEmma van DaalenWietske A EsterRob RiekenGwen C DielemanDaphne van AltenaBeatrijs BarteldsRon H N van SchaikKazem NasserinejadManon H J HillegersTeun van GelderBram DierckxBirgit C P KochPublished in: British journal of clinical pharmacology (2020)
Our results indicate a therapeutic window exists, which suggests that therapeutic drug monitoring of risperidone might increase safety and effectiveness in children and adolescents with ASD and behavioural problems.