SARS-CoV-2 first contact: Spike-ACE2 interactions in COVID-19.

Published in: Chemical biology & drug design (2021)

The full-length human ACE2 in complex with B0 AT1 is anchored to two S in open pre-fusion state which allows establishing pre-invasion interactions with the ACE2 N-terminal domain.

Keyphrases

sars cov
angiotensin converting enzyme
angiotensin ii
endothelial cells
coronavirus disease
respiratory syndrome coronavirus
minimally invasive
induced pluripotent stem cells
pluripotent stem cells