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Sunvozertinib, a Selective EGFR Inhibitor for Previously Treated Non-Small Cell Lung Cancer with EGFR Exon 20 Insertion Mutations.

Mengzhao WangJames Chih-Hsin YangPaul L MitchellJian FangD Ross CamidgeWeiqi NianChao-Hua ChiuJianying ZhouYanqiu ZhaoWu-Chou SuTsung-Ying YangViola W ZhuMichael MillwardYun FanWen-Tsung HuangYing ChengLiyan JiangDaniel BrungsLyudmila BazhenovaChee Khoon LeeBo GaoYan XuWei-Hsun HsuLi ZhengPasi A Janne
Published in: Cancer discovery (2022)
We report the discovery and early clinical development of sunvozertinib, a potential treatment option for the unmet medical need of EGFRexon20ins NSCLC. This article is highlighted in the In This Issue feature, p. 1599.
Keyphrases
  • small cell lung cancer
  • epidermal growth factor receptor
  • tyrosine kinase
  • healthcare
  • advanced non small cell lung cancer
  • small molecule
  • machine learning
  • high throughput
  • replacement therapy
  • climate change