Experimental design of preclinical experiments: number of PDX lines vs subsampling within PDX lines.
Jeanette E Eckel-PassowGaspar J KitangePaul A DeckerMatthew L KoselDanielle M BurgenskeAnn L ObergJann N SarkariaPublished in: Neuro-oncology (2022)
Experimental designs using few mice across many PDX lines can provide robust results and account for inter-tumor variability.