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Experimental design of preclinical experiments: number of PDX lines vs subsampling within PDX lines.

Jeanette E Eckel-PassowGaspar J KitangePaul A DeckerMatthew L KoselDanielle M BurgenskeAnn L ObergJann N Sarkaria
Published in: Neuro-oncology (2022)
Experimental designs using few mice across many PDX lines can provide robust results and account for inter-tumor variability.
Keyphrases
  • high fat diet induced
  • type diabetes
  • stem cells
  • skeletal muscle