Jann N Sarkaria

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 49

Top Topics

Tyrosine Kinase

Top Venues

Nature communications

Clinical cancer research : an official journal of the American Association for Cancer Research

Molecular cancer therapeutics

This page only lists publications with an associated author ORCID identifier.

Publications

Catherine A Behrmann, Kelli N Ennis, Pranjal Sarma, Collin Wetzel, Nicholas A Clark, Kate M Von Handorf, Subrahmanya Vallabhapurapu, Cristina Andreani, James Reigle, Pier Paolo Scaglioni, Jaroslaw Meller, Maria F Czyzyk-Krzeska, Ady Kendler, Xiaoyang Qi, Jann N Sarkaria, Mario Medvedovic, Soma Sengupta, Biplab DasGupta, David R Plas
Coordinated Targeting of S6K1/2 and AXL Disrupts Pyrimidine Biosynthesis in PTEN-Deficient Glioblastoma. Cancer research communications 4 (8) (2024)
Jiajia Chen, Daniel J Laverty, Surabhi Talele, Ashwin Bale, Brett L Carlson, Kendra A Porath, Katrina K Bakken, Danielle M Burgenske, Paul A Decker, Rachael Ann Vaubel, Jeanette E Eckel-Passow, Rohit Bhargava, Zhenkun Lou, Petra Hamerlik, Brendan A C Harley, William F Elmquist, Zachary D Nagel, Shiv K Gupta, Jann N Sarkaria
Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization. Science translational medicine 16 (734) (2024)
Sonia Jain, Jessica I Griffith, Kendra A Porath, Sneha Rathi, Jiayan Le, Tugce I Pasa, Paul A Decker, Shiv K Gupta, Zeng Hu, Brett L Carlson, Katrina K Bakken, Danielle M Burgenske, Thomas M Feldsien, Didier R Lefebvre, Rachael Ann Vaubel, Jeanette E Eckel-Passow, Edward B Reilly, William F Elmquist, Jann N Sarkaria
Bystander Effects, Pharmacokinetics, and Linker-Payload Stability of EGFR-Targeting Antibody-Drug Conjugates Losatuxizumab Vedotin and Depatux-M in Glioblastoma Models. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (15) (2024)
Jiajia Chen, Daniel J Laverty, Surabhi Talele, Ashwin Bale, Brett L Carlson, Kendra A Porath, Katrina K Bakken, Danielle M Burgenske, Paul A Decker, Rachael Ann Vaubel, Jeanette E Eckel-Passow, Rohit Bhargava, Zhenkun Lou, Petra Hamerlik, Brendan A C Harley, William F Elmquist, Zachary D Nagel, Shiv K Gupta, Jann N Sarkaria
Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization. Science translational medicine 16 (734) (2024)
Jiajia Chen, Daniel J Laverty, Surabhi Talele, Ashwin Bale, Brett L Carlson, Kendra A Porath, Katrina K Bakken, Danielle M Burgenske, Paul A Decker, Rachael Ann Vaubel, Jeanette E Eckel-Passow, Rohit Bhargava, Zhenkun Lou, Petra Hamerlik, Brendan A C Harley, William F Elmquist, Zachary D Nagel, Shiv K Gupta, Jann N Sarkaria
Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization. Science translational medicine 16 (734) (2024)
Daniel J Laverty, Shiv K Gupta, Gary A Bradshaw, Alexander S Hunter, Brett L Carlson, Nery Matias Calmo, Jiajia Chen, Shulan Tian, Jann N Sarkaria, Zachary D Nagel
ATM inhibition exploits checkpoint defects and ATM-dependent double strand break repair in TP53-mutant glioblastoma. Nature communications 15 (1) (2024)
Jianxiang Ji, Sonja Dragojevic, Cameron M Callaghan, Emily J Smith, Surabhi Talele, Wenjuan Zhang, Margaret A Connors, Ann C Mladek, Zeng Hu, Katrina K Bakken, Paige P Sarkaria, Brett L Carlson, Danielle M Burgenske, Paul A Decker, Mohammad Abdur Rashid, Mi-Hyeon Jang, Shiv K Gupta, Jeanette E Eckel-Passow, William F Elmquist, Jann N Sarkaria
Differential distribution of the DNA-PKcs inhibitor peposertib selectively radiosensitizes patient-derived melanoma brain metastasis xenografts. Molecular cancer therapeutics (2024)
Jiajia Chen, Daniel J Laverty, Surabhi Talele, Ashwin Bale, Brett L Carlson, Kendra A Porath, Katrina K Bakken, Danielle M Burgenske, Paul A Decker, Rachael Ann Vaubel, Jeanette E Eckel-Passow, Rohit Bhargava, Zhenkun Lou, Petra Hamerlik, Brendan A C Harley, William F Elmquist, Zachary D Nagel, Shiv K Gupta, Jann N Sarkaria
Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization. Science translational medicine 16 (734) (2024)
Catherine A Behrmann, Kelli N Ennis, Pranjal Sarma, Collin Wetzel, Nicholas A Clark, Kate M Von Handorf, Subrahmanya Vallabhapurapu, Cristina Andreani, James Reigle, Pier Paolo Scaglioni, Jaroslaw Meller, Maria F Czyzyk-Krzeska, Ady Kendler, Xiaoyang Qi, Jann N Sarkaria, Mario Medvedovic, Soma Sengupta, Biplab DasGupta, David R Plas
Coordinated Targeting of S6K1/2 and AXL Disrupts Pyrimidine Biosynthesis in PTEN-Deficient Glioblastoma. Cancer research communications 4 (8) (2024)
Jianxiang Ji, Sonja Dragojevic, Cameron M Callaghan, Emily J Smith, Surabhi Talele, Wenjuan Zhang, Margaret A Connors, Ann C Mladek, Zeng Hu, Katrina K Bakken, Paige P Sarkaria, Brett L Carlson, Danielle M Burgenske, Paul A Decker, Mohammad Abdur Rashid, Mi-Hyeon Jang, Shiv K Gupta, Jeanette E Eckel-Passow, William F Elmquist, Jann N Sarkaria
Differential Distribution of the DNA-PKcs Inhibitor Peposertib Selectively Radiosensitizes Patient-derived Melanoma Brain Metastasis Xenografts. Molecular cancer therapeutics 23 (5) (2024)
Catherine A Behrmann, Kelli N Ennis, Pranjal Sarma, Collin Wetzel, Nicholas A Clark, Kate M Von Handorf, Subrahmanya Vallabhapurapu, Cristina Andreani, James Reigle, Pier Paolo Scaglioni, Jaroslaw Meller, Maria F Czyzyk-Krzeska, Ady Kendler, Xiaoyang Qi, Jann N Sarkaria, Mario Medvedovic, Soma Sengupta, Biplab DasGupta, David R Plas
Coordinated Targeting of S6K1/2 and AXL Disrupts Pyrimidine Biosynthesis in PTEN-Deficient Glioblastoma. Cancer research communications 4 (8) (2024)
Jianxiang Ji, Sonja Dragojevic, Cameron M Callaghan, Emily J Smith, Surabhi Talele, Wenjuan Zhang, Margaret A Connors, Ann C Mladek, Zeng Hu, Katrina K Bakken, Paige P Sarkaria, Brett L Carlson, Danielle M Burgenske, Paul A Decker, Mohammad Abdur Rashid, Mi-Hyeon Jang, Shiv K Gupta, Jeanette E Eckel-Passow, William F Elmquist, Jann N Sarkaria
Differential distribution of the DNA-PKcs inhibitor peposertib selectively radiosensitizes patient-derived melanoma brain metastasis xenografts. Molecular cancer therapeutics (2024)
Daniel J Laverty, Shiv K Gupta, Gary A Bradshaw, Alexander S Hunter, Brett L Carlson, Nery Matias Calmo, Jiajia Chen, Shulan Tian, Jann N Sarkaria, Zachary D Nagel
ATM inhibition exploits checkpoint defects and ATM-dependent double strand break repair in TP53-mutant glioblastoma. Nature communications 15 (1) (2024)
Catherine A Behrmann, Kelli N Ennis, Pranjal Sarma, Collin Wetzel, Nicholas A Clark, Kate M Von Handorf, Subrahmanya Vallabhapurapu, Cristina Andreani, James Reigle, Pier Paolo Scaglioni, Jaroslaw Meller, Maria F Czyzyk-Krzeska, Ady Kendler, Xiaoyang Qi, Jann N Sarkaria, Mario Medvedovic, Soma Sengupta, Biplab DasGupta, David R Plas
Coordinated targeting of S6K1/2 and AXL disrupts pyrimidine biosynthesis in PTEN-deficient glioblastoma. Cancer research communications (2024)
Sonia Jain, Jessica I Griffith, Kendra A Porath, Sneha Rathi, Jiayan Le, Tugce I Pasa, Paul A Decker, Shiv K Gupta, Zeng Hu, Brett L Carlson, Katrina K Bakken, Danielle M Burgenske, Thomas M Feldsien, Didier R Lefebvre, Rachael Ann Vaubel, Jeanette E Eckel-Passow, Edward B Reilly, William F Elmquist, Jann N Sarkaria
Bystander Effects, Pharmacokinetics, and Linker-Payload Stability of EGFR-Targeting Antibody-Drug Conjugates Losatuxizumab Vedotin and Depatux-M in Glioblastoma Models. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (15) (2024)
Sonia Jain, Jessica I Griffith, Kendra A Porath, Sneha Rathi, Jiayan Le, Tugce I Pasa, Paul A Decker, Shiv K Gupta, Zeng Hu, Brett L Carlson, Katrina K Bakken, Danielle M Burgenske, Thomas M Feldsien, Didier R Lefebvre, Rachael Ann Vaubel, Jeanette E Eckel-Passow, Edward B Reilly, William F Elmquist, Jann N Sarkaria
Bystander effects, pharmacokinetics, and linker-payload stability of EGFR-targeting antibody-drug conjugates Losatuxizumab vedotin and Depatux-M in glioblastoma models. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Jiajia Chen, Daniel J Laverty, Surabhi Talele, Ashwin Bale, Brett L Carlson, Kendra A Porath, Katrina K Bakken, Danielle M Burgenske, Paul A Decker, Rachael Ann Vaubel, Jeanette E Eckel-Passow, Rohit Bhargava, Zhenkun Lou, Petra Hamerlik, Brendan A C Harley, William F Elmquist, Zachary D Nagel, Shiv K Gupta, Jann N Sarkaria
Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization. Science translational medicine 16 (734) (2024)
Jiajia Chen, Daniel J Laverty, Surabhi Talele, Ashwin Bale, Brett L Carlson, Kendra A Porath, Katrina K Bakken, Danielle M Burgenske, Paul A Decker, Rachael Ann Vaubel, Jeanette E Eckel-Passow, Rohit Bhargava, Zhenkun Lou, Petra Hamerlik, Brendan A C Harley, William F Elmquist, Zachary D Nagel, Shiv K Gupta, Jann N Sarkaria
Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization. Science translational medicine 16 (734) (2024)
Jianxiang Ji, Sonja Dragojevic, Cameron M Callaghan, Emily J Smith, Surabhi Talele, Wenjuan Zhang, Margaret A Connors, Ann C Mladek, Zeng Hu, Katrina K Bakken, Paige P Sarkaria, Brett L Carlson, Danielle M Burgenske, Paul A Decker, Mohammad Abdur Rashid, Mi-Hyeon Jang, Shiv K Gupta, Jeanette E Eckel-Passow, William F Elmquist, Jann N Sarkaria
Differential Distribution of the DNA-PKcs Inhibitor Peposertib Selectively Radiosensitizes Patient-derived Melanoma Brain Metastasis Xenografts. Molecular cancer therapeutics 23 (5) (2024)
Jianxiang Ji, Sonja Dragojevic, Cameron M Callaghan, Emily J Smith, Surabhi Talele, Wenjuan Zhang, Margaret A Connors, Ann C Mladek, Zeng Hu, Katrina K Bakken, Paige P Sarkaria, Brett L Carlson, Danielle M Burgenske, Paul A Decker, Mohammad Abdur Rashid, Mi-Hyeon Jang, Shiv K Gupta, Jeanette E Eckel-Passow, William F Elmquist, Jann N Sarkaria
Differential Distribution of the DNA-PKcs Inhibitor Peposertib Selectively Radiosensitizes Patient-derived Melanoma Brain Metastasis Xenografts. Molecular cancer therapeutics 23 (5) (2024)
Daniel J Laverty, Shiv K Gupta, Gary A Bradshaw, Alexander S Hunter, Brett L Carlson, Nery Matias Calmo, Jiajia Chen, Shulan Tian, Jann N Sarkaria, Zachary D Nagel
ATM inhibition exploits checkpoint defects and ATM-dependent double strand break repair in TP53-mutant glioblastoma. Nature communications 15 (1) (2024)
Jianxiang Ji, Sonja Dragojevic, Cameron M Callaghan, Emily J Smith, Surabhi Talele, Wenjuan Zhang, Margaret A Connors, Ann C Mladek, Zeng Hu, Katrina K Bakken, Paige P Sarkaria, Brett L Carlson, Danielle M Burgenske, Paul A Decker, Mohammad Abdur Rashid, Mi-Hyeon Jang, Shiv K Gupta, Jeanette E Eckel-Passow, William F Elmquist, Jann N Sarkaria
Differential Distribution of the DNA-PKcs Inhibitor Peposertib Selectively Radiosensitizes Patient-derived Melanoma Brain Metastasis Xenografts. Molecular cancer therapeutics 23 (5) (2024)
Sonia Jain, Jessica I Griffith, Kendra A Porath, Sneha Rathi, Jiayan Le, Tugce I Pasa, Paul A Decker, Shiv K Gupta, Zeng Hu, Brett L Carlson, Katrina K Bakken, Danielle M Burgenske, Thomas M Feldsien, Didier R Lefebvre, Rachael Ann Vaubel, Jeanette E Eckel-Passow, Edward B Reilly, William F Elmquist, Jann N Sarkaria
Bystander Effects, Pharmacokinetics, and Linker-Payload Stability of EGFR-Targeting Antibody-Drug Conjugates Losatuxizumab Vedotin and Depatux-M in Glioblastoma Models. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (15) (2024)
Sonia Jain, Jessica I Griffith, Kendra A Porath, Sneha Rathi, Jiayan Le, Tugce I Pasa, Paul A Decker, Shiv K Gupta, Zeng Hu, Brett L Carlson, Katrina K Bakken, Danielle M Burgenske, Thomas M Feldsien, Didier R Lefebvre, Rachael Ann Vaubel, Jeanette E Eckel-Passow, Edward B Reilly, William F Elmquist, Jann N Sarkaria
Bystander Effects, Pharmacokinetics, and Linker-Payload Stability of EGFR-Targeting Antibody-Drug Conjugates Losatuxizumab Vedotin and Depatux-M in Glioblastoma Models. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (15) (2024)
Simona Migliozzi, Young Taek Oh, Mohammad Hasanain, Luciano Garofano, Fulvio D'Angelo, Ryan D Najac, Alberto Picca, Franck Bielle, Anna-Luisa Di Stefano, Julie Lerond, Jann N Sarkaria, Michele Ceccarelli, Marc Sanson, Anna Lasorella, Antonio Iavarone
Integrative multi-omics networks identify PKCδ and DNA-PK as master kinases of glioblastoma subtypes and guide targeted cancer therapy. Nature cancer 4 (2) (2023)
Simona Migliozzi, Young Taek Oh, Mohammad Hasanain, Luciano Garofano, Fulvio D'Angelo, Ryan D Najac, Alberto Picca, Franck Bielle, Anna-Luisa Di Stefano, Julie Lerond, Jann N Sarkaria, Michele Ceccarelli, Marc Sanson, Anna Lasorella, Antonio Iavarone
Integrative multi-omics networks identify PKCδ and DNA-PK as master kinases of glioblastoma subtypes and guide targeted cancer therapy. Nature cancer (2023)
Wenjuan Zhang, Rachael Ann Vaubel, Ju-Hee Oh, Ann C Mladek, Surabhi Talele, Wenqiu Zhang, Katie L Waller, Danielle M Burgenske, Jann N Sarkaria, William F Elmquist
Delivery versus potency in treating brain tumors: BI-907828, a MDM2-p53 antagonist with limited BBB penetration but significant in vivo efficacy in glioblastoma. Molecular cancer therapeutics (2023)
Simona Migliozzi, Young Taek Oh, Mohammad Hasanain, Luciano Garofano, Fulvio D'Angelo, Ryan D Najac, Alberto Picca, Franck Bielle, Anna-Luisa Di Stefano, Julie Lerond, Jann N Sarkaria, Michele Ceccarelli, Marc Sanson, Anna Lasorella, Antonio Iavarone
Integrative multi-omics networks identify PKCδ and DNA-PK as master kinases of glioblastoma subtypes and guide targeted cancer therapy. Nature cancer 4 (2) (2023)
Simona Migliozzi, Young Taek Oh, Mohammad Hasanain, Luciano Garofano, Fulvio D'Angelo, Ryan D Najac, Alberto Picca, Franck Bielle, Anna-Luisa Di Stefano, Julie Lerond, Jann N Sarkaria, Michele Ceccarelli, Marc Sanson, Anna Lasorella, Antonio Iavarone
Integrative multi-omics networks identify PKCδ and DNA-PK as master kinases of glioblastoma subtypes and guide targeted cancer therapy. Nature cancer 4 (2) (2023)
Simona Migliozzi, Young Taek Oh, Mohammad Hasanain, Luciano Garofano, Fulvio D'Angelo, Ryan D Najac, Alberto Picca, Franck Bielle, Anna-Luisa Di Stefano, Julie Lerond, Jann N Sarkaria, Michele Ceccarelli, Marc Sanson, Anna Lasorella, Antonio Iavarone
Integrative multi-omics networks identify PKCδ and DNA-PK as master kinases of glioblastoma subtypes and guide targeted cancer therapy. Nature cancer 4 (2) (2023)
Michael S Petronek, Varun V Monga, Kellie L Bodeker, Michael Kwofie, Chu-Yu Lee, Kranti A Mapuskar, Jeffrey M Stolwijk, Amira Zaher, Brett A Wagner, Mark C Smith, Sandy Vollstedt, Heather Brown, Meghan L Chandler, Amanda C Lorack, Jared S Wulfekuhle, Jann N Sarkaria, Ryan T Flynn, Jeremy D W Greenlee, Matthew A Howard, Brian J Smith, Karra A Jones, Garry R Buettner, Joseph J Cullen, Joel J St-Aubin, John M Buatti, Vincent A Magnotta, Douglas R Spitz, Bryan G Allen
Magnetic resonance imaging of iron metabolism with T2* mapping predicts an enhanced clinical response to pharmacological ascorbate in patients with GBM. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Anna D Staniszewska, Domenic Pilger, Sonja J Gill, Kunzah Jamal, Natacha Bohin, Sofia Guzzetti, Jacob A Gordon, Gregory Hamm, Gill Mundin, Giuditta Illuzzi, Andy Pike, Lisa McWilliams, Gareth A Maglennon, Jonathan Rose, Glen Hawthorne, Miguel A Cortés González, Christer Halldin, Peter Johnström, Magnus Schou, Susan E Critchlow, Stephen E Fawell, Jeffrey W Johannes, Elisabetta Leo, Barry R Davies, Sabina Cosulich, Jann N Sarkaria, Lenka Oplustil O'Connor, Petra Hamerlik
Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Weihua Zhou, Zitong Zhao, Angelica Lin, John Z Yang, Jie Xu, Kari Wilder-Romans, Annabel Yang, Jing Li, Sumeet Solanki, Jennifer M Speth, Natalie Walker, Andrew J Scott, Lu Wang, Bo Wen, Anthony Andren, Li Zhang, Ayesha U Kothari, Yangyang Yao, Erik R Peterson, Navyateja Korimerla, Christian K Werner, Alexander Ullrich, Jessica Liang, Janna Jacobson, Sravya Palavalasa, Alexandra M O'Brien, Ameer L Elaimy, Sean P Ferris, Shuang G Zhao, Jann N Sarkaria, Gyorffy Balazs, Shuqun Zhang, Wajd N Al-Holou, Yoshie Umemura, Meredith A Morgan, Theodore S Lawrence, Costas Andreas Lyssiotis, Marc Peters-Golden, Yatrik M Shah, Daniel R Wahl
GTP signaling links metabolism, DNA repair, and responses to genotoxic stress. Cancer discovery (2023)
Cecile Riviere-Cazaux, Lucas P Carlstrom, Karishma Rajani, Amanda Munoz-Casabella, Masum Rahman, Ali Gharibi-Loron, Desmond A Brown, Kai J Miller, Jaclyn J White, Benjamin T Himes, Ignacio Jusue-Torres, Samar Ikram, Seth C Ransom, Renee Hirte, Ju-Hee Oh, William F Elmquist, Jann N Sarkaria, Rachael Ann Vaubel, Moses Rodriguez, Arthur E Warrington, Sani H Kizilbash, Terry C Burns
Blood-brain barrier disruption defines the extracellular metabolome of live human high-grade gliomas. Communications biology 6 (1) (2023)
Simona Migliozzi, Young Taek Oh, Mohammad Hasanain, Luciano Garofano, Fulvio D'Angelo, Ryan D Najac, Alberto Picca, Franck Bielle, Anna-Luisa Di Stefano, Julie Lerond, Jann N Sarkaria, Michele Ceccarelli, Marc Sanson, Anna Lasorella, Antonio Iavarone
Integrative multi-omics networks identify PKCδ and DNA-PK as master kinases of glioblastoma subtypes and guide targeted cancer therapy. Nature cancer 4 (2) (2023)
Simona Migliozzi, Young Taek Oh, Mohammad Hasanain, Luciano Garofano, Fulvio D'Angelo, Ryan D Najac, Alberto Picca, Franck Bielle, Anna-Luisa Di Stefano, Julie Lerond, Jann N Sarkaria, Michele Ceccarelli, Marc Sanson, Anna Lasorella, Antonio Iavarone
Integrative multi-omics networks identify PKCδ and DNA-PK as master kinases of glioblastoma subtypes and guide targeted cancer therapy. Nature cancer (2023)
Shannon P Fortin Ensign, Robert B Jenkins, Caterina Giannini, Jann N Sarkaria, Evanthia Galanis, Sani H Kizilbash
Translational Significance of CDKN2A/B Homozygous Deletion in IDH-Mutant Astrocytoma. Neuro-oncology (2022)
Masum Rahman, Ian Olson, Moustafa Mansour, Lucas P Carlstrom, Rujapope Sutiwisesak, Rehan Saber, Karishma Rajani, Arthur E Warrington, Adam Howard, Mark Schroeder, Sisi Chen, Paul A Decker, Eliot F Sananikone, Yi Zhu, Tamar Tchkonia, Ian F Parney, Sandeep Burma, Desmond A Brown, Moses Rodriguez, Jann N Sarkaria, James L Kirkland, Terry C Burns
Selective Vulnerability of Senescent Glioblastoma Cells to BCL-XL Inhibition. Molecular cancer research : MCR 20 (6) (2022)
Ann C Mladek, Huihuang Yan, Shulan Tian, Paul A Decker, Danielle M Burgenske, Katrina Bakken, Zeng Hu, Lihong He, Margaret A Connors, Brett L Carlson, Jonathan Wilson, Archana Bommi-Reddy, Andy Conery, Jeanette E Eckel-Passow, Jann N Sarkaria, Gaspar J Kitange
RBBP4-p300 axis modulates expression of genes essential for cell survival and is a potential target for therapy in glioblastoma. Neuro-oncology 24 (8) (2022)
Jeanette E Eckel-Passow, Gaspar J Kitange, Paul A Decker, Matthew L Kosel, Danielle M Burgenske, Ann L Oberg, Jann N Sarkaria
Experimental design of preclinical experiments: number of PDX lines vs subsampling within PDX lines. Neuro-oncology 23 (12) (2022)
Paul Daniel, Brian Meehan, Siham Sabri, Fatemeh Jamali, Jann N Sarkaria, Dongsic Choi, Delphine Garnier, Gaspar Kitange, Kate I Glennon, Antoine Paccard, Jason Karamchandani, Yasser Riazalhosseini, Janusz Rak, Bassam Abdulkarim
Detection of temozolomide-induced hypermutation and response to PD-1 checkpoint inhibitor in recurrent glioblastoma. Neuro-oncology advances 4 (1) (2022)
Thomas S C Ng, Hui-Yu Hu, Stefan Kronister, Chanseo Lee, Ran Li, Luca Gerosa, Sylwia A Stopka, Danielle M Burgenske, Ishaan Khurana, Michael S Regan, Sreeram Vallabhaneni, Niharika Putta, Ella Scott, Dylan Matvey, Anita Giobbie-Hurder, Rainer H Kohler, Jann N Sarkaria, Sareh Parangi, Peter Karl Sorger, Nathalie Y R Agar, Heather A Jacene, Ryan J Sullivan, Elizabeth Buchbinder, Hannes Mikula, Ralph Weissleder, Miles A Miller
Overcoming differential tumor penetration of BRAF inhibitors using computationally guided combination therapy. Science advances 8 (17) (2022)
Walid M Abdelmoula, Begona Gimenez-Cassina Lopez, Elizabeth C Randall, Tina Kapur, Jann N Sarkaria, Forest M White, Jeffery N Agar, William M Wells, Nathalie Y R Agar
Peak learning of mass spectrometry imaging data using artificial neural networks. Nature communications 12 (1) (2021)
Laetitia Seguin, Soline Odouard, Francesca Corlazzoli, Sarah Al Haddad, Laurine Moindrot, Marta Calvo Tardón, Mayra Yebra, Alexey Koval, Eliana Marinari, Viviane Bes, Alexandre Guérin, Mathilde Allard, Sten Ilmjärv, Vladimir L Katanaev, Paul R Walker, Karl-Heinz Krause, Valérie Dutoit, Jann N Sarkaria, Pierre-Yves Dietrich, Érika Cosset
Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cells. Communications biology 4 (1) (2021)
Silvia Pietrobono, Giulia Anichini, Cesare Sala, Fabrizio Manetti, Luciana L Almada, Sara Pepe, Ryan M Carr, Brooke D Paradise, Jann N Sarkaria, Jaime I Davila, Lorenzo Tofani, Ilaria Battisti, Giorgio Arrigoni, Li Ying, Cheng Zhang, Hu Li, Alexander Meves, Martin E Fernandez-Zapico, Barbara Stecca
ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL. Nature communications 11 (1) (2020)
Jaclyn J Renfrow, Michael H Soike, James L West, Shakti H Ramkissoon, Linda Metheny-Barlow, Ryan T Mott, Carol A Kittel, Ralph B D'Agostino, Stephen B Tatter, Adrian W Laxton, Mark B Frenkel, Gregory A Hawkins, Denise Herpai, Stephanie Sanders, Jann N Sarkaria, Glenn J Lesser, Waldemar Debinski, Roy E Strowd
Attenuating hypoxia driven malignant behavior in glioblastoma with a novel hypoxia-inducible factor 2 alpha inhibitor. Scientific reports 10 (1) (2020)
Weihua Zhou, Yangyang Yao, Andrew J Scott, Kari Wilder-Romans, Joseph J Dresser, Christian K Werner, Hanshi Sun, Drew Pratt, Peter Sajjakulnukit, Shuang G Zhao, Mary Davis, Barbara S Nelson, Christopher J Halbrook, Li Zhang, Francesco Gatto, Yoshie Umemura, Angela K Walker, Maureen Kachman, Jann N Sarkaria, Jianping Xiong, Meredith A Morgan, Alnawaz Rehemtualla, Maria Graciela Castro, Pedro R Lowenstein, Sriram Chandrasekaran, Theodore S Lawrence, Costas Andreas Lyssiotis, Daniel R Wahl
Purine metabolism regulates DNA repair and therapy resistance in glioblastoma. Nature communications 11 (1) (2020)
Kate Connor, David W Murray, Monika A Jarzabek, Nhan L Tran, Kieron White, Patrick Dicker, Kieron J Sweeney, Philip J O'Halloran, Brian MacCarthy, Liam P Shiels, Francesca Lodi, Diether Lambrechts, Jann N Sarkaria, Raymond M Schiffelers, Marc Symons, Annette T Byrne
Targeting the RhoGEF βPIX/COOL-1 in Glioblastoma: Proof of Concept Studies. Cancers 12 (12) (2020)
Vasileios Stathias, Anna M Jermakowicz, Marie E Maloof, Michele Forlin, Winston Walters, Robert K Suter, Michael A Durante, Sion L Williams, J William Harbour, Claude-Henry Volmar, Nicholas J Lyons, Claes Wahlestedt, Regina M Graham, Michael E Ivan, Ricardo J Komotar, Jann N Sarkaria, Aravind Subramanian, Todd R Golub, Stephan C Schürer, Nagi G Ayad
Drug and disease signature integration identifies synergistic combinations in glioblastoma. Nature communications 9 (1) (2018)