PathCORE-T: identifying and visualizing globally co-occurring pathways in large transcriptomic compendia.

Kathleen M Chen Jie Tan Gregory P Way Georgia Doing Deborah Ann Hogan Casey S Greene

Published in: BioData mining (2018)

The PathCORE-T framework identifies transcriptionally co-occurring pathways from the results of unsupervised analysis of gene expression data and visualizes the relationships between pathways as a network. PathCORE-T recapitulated previously described pathway-pathway relationships and suggested experimentally testable additional hypotheses that remain to be explored.

Keyphrases

gene expression
machine learning
dna methylation
genome wide
single cell