PAX-D: study protocol for a randomised placebo-controlled trial evaluating the efficacy and mechanism of pramipexole as add-on treatment for people with treatment resistant depression.

Sheena Kristine Au-YeungJames GriffithsSophie RobertsChloe EdwardsLy-Mee YuRafal BogaczJennifer RendellMary-Jane AttenburrowStuart WatsonFiona ChanAndrea CiprianiAnthony CleareCatherine J HarmerDavid KesslerJonathan EvansGlyn LewisIlina SinghJudit SimonPaul J HarrisonPhil CowenMilensu ShanyindeJohn GeddesMichael Browning

Published in: Evidence-based mental health (2021)

ISRCTN84666271.

Keyphrases

double blind
clinical trial
study protocol
open label
depressive symptoms
randomized controlled trial
placebo controlled
sleep quality
replacement therapy