Identification of Novel Insulin Resistance Related ceRNA Network in T2DM and Its Potential Editing by CRISPR/Cas9.

Marwa Matboli Marwa Mostafa KamelNada EssawyMeram Mohamed BekhitBasant AbdulrahmanGhada F MohamedSanaa Eissa

Published in: International journal of molecular sciences (2021)

The present study provides the significance of this ceRNA based network and its related target genes panel both in the pathogenesis of insulin resistance and as a therapeutic target for gene editing in T2DM.

Keyphrases

crispr cas
insulin resistance
genome editing
long non coding rna
adipose tissue
type diabetes
metabolic syndrome
polycystic ovary syndrome
glycemic control
skeletal muscle
bioinformatics analysis
genome wide
network analysis