Modulation of anterior cingulate cortex reward and penalty signalling in medication-naive young-adult subjects with depressive symptoms following acute dose lurasidone.
Selina A WolkeMitul A MehtaOwen O'DalyFernando ZelayaNada ZahreddineHanna KerenGeorgia O'CallaghanAllan H YoungEllen LeibenluftDaniel S PineArgyris StringarisPublished in: Psychological medicine (2019)
Lurasidone acutely normalises reward processing signals in individuals with depressive symptoms. Lurasidone's antidepressant effects may arise from reducing responses to penalty outcomes in individuals with depressive symptoms.