Antiretroviral therapy provided to HIV-infected Malawian women in a randomized trial diminishes the positive effects of lipid-based nutrient supplements on breast-milk B vitamins.

Lindsay H AllenDaniela HampelSetareh Shahab-FerdowsEmily R YorkLinda S AdairValerie L FlaxGerald TeghaCharles S ChaselaDebbie KamwendoDenise J JamiesonMargaret E Bentley

Published in: The American journal of clinical nutrition (2015)

All B vitamins were low in milk, and all but thiamin were increased by maternal supplementation with LNSs. Antiretrovirals alone decreased concentrations of some B vitamins in milk. When LNS was given in addition to antiretrovirals, the negative effect of antiretrovirals offset the positive effect of LNSs for all vitamins except thiamin. This trial was registered at clinicaltrials.gov as NCT00164762.

Keyphrases

hiv infected
antiretroviral therapy
human immunodeficiency virus
hiv infected patients
hiv positive
pregnancy outcomes
hiv aids
clinical trial
type diabetes
pregnant women
randomized controlled trial
body mass index
skeletal muscle
hepatitis c virus