MDM2-C Functions as an E3 Ubiquitin Ligase.

Jun Yeob Kim Rusia Lee Gu Xiao Dominique Forbes Jill Bargonetti

Published in: Cancer management and research (2020)

This information strongly positions MDM2-C as a protein with biochemical activities that may explain the varied outcomes observed in patients with high-level expression of MDM2-C in the presence of wild-type p53 versus mutant p53.

Keyphrases

wild type
poor prognosis
health information
amino acid
metabolic syndrome
adipose tissue
skeletal muscle