Clinical effects of long-term cardiac contractility modulation (CCM) in subjects with heart failure caused by left ventricular systolic dysfunction.
David D GuttermanA RemppisP SchauerteS Schmidt-SchwedaD BurkhoffB RoussoD GuttermanJ SengesG HindricksK-H KuckPublished in: Clinical research in cardiology : official journal of the German Cardiac Society (2017)
Cardiac contractility modulation provides safe and effective long-term symptomatic and functional improvement in heart failure. These benefits were independent of baseline LVEF and were associated with a safety profile similar to published device trials.
Keyphrases
- left ventricular
- heart failure
- cardiac resynchronization therapy
- hypertrophic cardiomyopathy
- acute myocardial infarction
- left atrial
- aortic stenosis
- mitral valve
- smooth muscle
- blood pressure
- acute heart failure
- atrial fibrillation
- randomized controlled trial
- acute coronary syndrome
- coronary artery disease
- ejection fraction