s-dePooler: determination of polymorphism carriers from overlapping DNA pools.

Aleksandr Igorevich ZhernakovAlexey Mikhailovich AfoninNatalia Dmitrievna GavriliukOlga Mikhailovna MoiseevaVladimir Aleksandrovich Zhukov

Published in: BMC bioinformatics (2019)

s-dePooler along with dePoP can be used to identify carriers of polymorphisms in overlapping pools, and is compatible with any pooling scheme with equivalent molar ratios of pooled samples. s-dePooler and dePoP with usage instructions and test data are freely available at https://github.com/lab9arriam/depop .

Keyphrases

circulating tumor
electronic health record
cell free
big data
solid phase extraction
molecularly imprinted
randomized controlled trial
clinical trial
phase iii
mass spectrometry
machine learning
high resolution
artificial intelligence
deep learning
circulating tumor cells
study protocol
open label
double blind