The exciting potential and daunting challenge of using GPS human-mobility data for epidemic modeling.

Large-scale GPS location datasets hold immense potential for measuring human mobility and interpersonal contact, both of which are essential for data-driven epidemiology. However, despite their potential and widespread adoption during the COVID-19 pandemic, there are several challenges with these data that raise concerns regarding the validity and robustness of its applications. Here we outline two types of challenges-some related to accessing and processing these data, and some related to data quality-and propose several research directions to address them moving forward.