MILACC study: could undetected lymph node micrometastases have impacted recurrence rate in the LACC trial?
Roni Nitecki WilkePedro T RamirezPavel DundrKristyna NemejcovaReitan RibeiroMariano Tamura Vieira GomesRonaldo Luis SchmidtLucio BedoyaDavid Ortiz IslaLina CaicedoGabriel Jaime Rendón PereiraAldo Lopez BlancoDavid KushnerDavid CibulaPublished in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2023)
There were no lymph node low-volume metastases among patients with initially negative lymph nodes who recurred in the LACC trial. Therefore, it is unlikely that manipulation of lymph nodes containing clinically undetected metastases is the underlying cause of the higher local recurrence risk in the minimally invasive arm of the LACC trial.