Comparison of naltrexone implant and oral buprenorphine-naloxone in the treatment of opiate use disorder.

Ali Erdoğan Müge Topcuoğlu Mustafa Nogay Coşkun Buket Cinemre Burak Kulaksızoğlu Mehmet Murat Kuloğlu

Published in: Human psychopharmacology (2021)

These findings suggest that BUP-NX might be more effective than XR-NTX in preventing relapse in OUD and both drugs are safe for the liver. Prospective randomized studies are needed to replicate our results.

Keyphrases

double blind
open label
placebo controlled
phase iii
clinical trial
phase ii
randomized controlled trial
case control
soft tissue
study protocol