Effect of melatonin supplementation on endothelial function in heart failure with reduced ejection fraction: A randomized, double-blinded clinical trial.

Shervin Ghaffari HoseiniKiyan Heshmat-GhahdarijaniSaeid KhosrawiMohammad GarakyaraghiDavood ShafieHamidreza RoohafzaMarjan MansourianElham AziziYousof GheisariMasoumeh Sadeghi

Published in: Clinical cardiology (2021)

Melatonin supplementation in HFrEF might improve endothelial function; however, this beneficial effect might not be seen in diabetic patients.

Keyphrases

heart failure
clinical trial
phase ii
study protocol
open label
atrial fibrillation
randomized controlled trial
cardiac resynchronization therapy
phase iii