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Sexually dimorphic DNA methylation and gene expression patterns in human first trimester placenta.

Tania L GonzalezBryn E WillsonErica T WangKent D TaylorAllynson NovoaAkhila SwarnaJuanita C OrtizGianna J ZenoCaroline A JefferiesKate LawrensonJerome I RotterYii-Der Ida ChenJohn WilliamsJinrui CuiMark O GoodarziMargareta D Pisarska
Published in: Biology of sex differences (2024)
Overall, sex dimorphic differential methylation with associated differential gene expression in the first trimester placenta is small, but there remain significant genes that may be regulated through methylation leading to differences in the first trimester placenta.
Keyphrases
  • dna methylation
  • gene expression
  • genome wide
  • endothelial cells
  • copy number
  • transcription factor
  • pluripotent stem cells
  • genome wide analysis