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Prevalence of Exocrine Pancreatic Dysfunction Based on Direct Function Testing in Pediatric Inflammatory Bowel Disease.

Jenelle FernandezPuanani HopsonSamit B PatelKaroly HorvathAkash Pandey
Published in: Journal of pediatric gastroenterology and nutrition (2023)
This pilot study revealed a relatively high prevalence of EPI in children with IBD through use of ePFT. EPI can result in maldigestion, with decreased capacity to digest fat. Further prospective studies are needed to assess need and efficacy of pancreatic enzyme replacement therapy in children with IBD and abnormal ePFT.
Keyphrases
  • replacement therapy
  • young adults
  • ulcerative colitis
  • adipose tissue
  • smoking cessation
  • risk factors
  • oxidative stress
  • single cell
  • fatty acid