Extracellular Vesicles from Stromal Vascular Fraction of Human Adipose Tissue in the Development of Non-antibiotic Therapy.
Vani Murthy Halahalli SrinivasaMohana KumarPrakash PatilNikhil ShettyA Veena ShettyPublished in: Current drug targets (2023)
Additionally, the underlying science that explains how the inflammatory process aids in the clearance of infections and the restoration of homeostasis after the host immune system successfully defends against foreign pathogens, as well as the fact that adipose-derived SVF is a noninvasive, cost-effective source of a variety of parent immune cells that produces a good yield of EVs with the same genetic make-up as their parent cells, make this concept worthwhile. This research may thereby increase survival rates and survival quality in cases of resistant infections. Vocabulary: Drug- and cell-free therapy = Nano molecules (extracellular vesicles) used as a therapeutic source without the need for chemical drugs or cell transplantation. Anti-infection EVs (aEVs) = Nature's own anti-infection powered EVs (unmodified).
Keyphrases
- cell free
- adipose tissue
- cell therapy
- endothelial cells
- induced apoptosis
- oxidative stress
- single cell
- bone marrow
- cell cycle arrest
- insulin resistance
- high fat diet
- emergency department
- type diabetes
- genome wide
- stem cells
- cell proliferation
- endoplasmic reticulum stress
- signaling pathway
- quality improvement
- copy number
- pluripotent stem cells
- circulating tumor
- electronic health record
- circulating tumor cells