Inhibition of 5-Lipoxygenase-Derived Leukotrienes and Hemiketals as a Novel Anti-Inflammatory Mechanism of Urolithins.
Juan Antonio Giménez-BastidaAntonio González-SarríasJuan Carlos EspínClaus SchneiderPublished in: Molecular nutrition & food research (2020)
The results show that physiologically relevant colonic Uro target eicosanoid biosynthetic pathways. The effect on HKs and LTB4 formation is unprecedented and expands the knowledge on anti-inflammatory mechanisms of Uro against IBDs.
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