Multimodality Imaging Evaluation of Coronary IgG4-Related Disease: A "Tumor-Like" Cardiac Lesion.
Ludovica R M LanzafameMaria Ludovica CarerjGiovanna RizzoFabio MinutoliGiuseppe Mauro BucoloNatasha IrreraGiuseppe MuscogiuriSandro SironiAlfredo BlandinoTommaso D AngeloPublished in: Diagnostics (Basel, Switzerland) (2022)
Immunoglobulin G4-related disease (IgG4-RD) is a systemic immune-mediated fibro-inflammatory disorder. Coronary IgG4-RD has been scarcely reported and may present as "tumor-like" lesions. These pseudo-masses may be underdiagnosed mainly due to a vague clinical picture that can vary from complete lack of symptoms to acute coronary syndrome or sudden cardiac death. Early recognition of coronary IgG4-RD is essential to monitor disease activity and prevent life-threatening complications. We report a comprehensive non-invasive imaging evaluation of a patient affected by coronary IgG4-RD, which was diagnosed as an incidental finding during routine pre-laparoscopic cholecystectomy checkup. Non-invasive imaging revealed the presence of a peri-coronary soft-tissue mass that was stable at 12 months follow-up.
Keyphrases
- coronary artery disease
- coronary artery
- disease activity
- high resolution
- acute coronary syndrome
- rheumatoid arthritis
- systemic lupus erythematosus
- soft tissue
- ankylosing spondylitis
- percutaneous coronary intervention
- case report
- risk factors
- magnetic resonance
- rheumatoid arthritis patients
- magnetic resonance imaging
- computed tomography
- mass spectrometry
- physical activity
- drug induced