The acute effects of cannabis with and without cannabidiol in adults and adolescents: A randomised, double-blind, placebo-controlled, crossover experiment.
Will LawnKatie TrinciClaire MokryszAnna BorissovaShelan OforiKat PetrilliMichael BloomfieldZarah R HaniffDaniel HallNatalia Fernandez-VinsonSimiao WangAmir EnglundEdward ChesneyMatthew B WallTom P FreemanH Valerie CurranPublished in: Addiction (Abingdon, England) (2023)
Adolescent cannabis users are neither more resilient nor more vulnerable than adult cannabis users to the acute psychotomimetic, memory-impairing, or subjective effects of cannabis. Furthermore, in adolescents and adults, vaporised cannabidiol does not mitigate the acute harms caused by delta-9-tetrahydocannabinol.
Keyphrases
- placebo controlled
- double blind
- liver failure
- young adults
- respiratory failure
- clinical trial
- drug induced
- study protocol
- aortic dissection
- physical activity
- open label
- phase ii
- phase iii
- hepatitis b virus
- phase ii study
- randomized controlled trial
- intensive care unit
- extracorporeal membrane oxygenation
- radiation therapy