Reduced Influenza B-Specific Postvaccination Antibody Cross-reactivity in the B/Victoria Lineage-Predominant 2019/20 Season.
Hang XieRuoxuan XiangHamilton J WanEwan P PlantPeter RadvakMartina KosikovaXing LiOlga ZouevaZhiping YeXiu-Feng WanPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
Our results indicate that postvaccination antibodies induced by the B/Vic vaccine component of the 2019/20 influenza season had reduced HAI cross-reactivity toward predominant 3DEL viruses in the United States. A close monitoring of the 3DEL 136E+150K subgroup is warranted should this subgroup return and predominate the 2020/21 influenza season.